What is the typical methotrexate dosing for rheumatoid arthritis?

The typical dosing of methotrexate for rheumatoid arthritis usually falls within the range of 5 to 25 mg weekly. Methotrexate is commonly used as a disease-modifying antirheumatic drug (DMARD) in the treatment of rheumatoid arthritis, and this dosing range allows for effective management of symptoms while minimizing potential side effects.

The lower end of the range (5 mg weekly) may be appropriate for initial therapy or for patients who are more sensitive to medications, whereas the higher end (up to 25 mg weekly) may be utilized for individuals who require a stronger therapeutic effect. It’s important for clinicians to start at lower doses and adjust based on the patient's response and tolerance to the medication. Regular monitoring for side effects and overall effectiveness is also a key component when using methotrexate for rheumatoid arthritis.