Vinca alkaloids must be administered via which route?

Vinca alkaloids, a class of chemotherapy drugs, are specifically designed to be administered intravenously. This delivery method is crucial because the drugs are highly toxic if administered through other routes. When administered intravenously, they don't go through the liver's first-pass metabolism, allowing for better therapeutic levels in the bloodstream.

Moreover, intravenous administration helps to avoid the complications that can arise with intramuscular or subcutaneous injections, such as painful local tissue damage and potential necrosis. It is vital to follow the proper intravenous route to maintain the efficacy of the treatment and minimize the risk of adverse effects, which is why this route is required for vinca alkaloids.